Seth Reine, Holden Archer, Ahmed Alshaikhsalama, Joel Wells, Ajay Kohli, Louis Vasquez, Allan Hummer, Matthew DiFranco, Richard Ljuhar, Yin Xi and Avneesh Chhabra
Adv. Artif. Intell. Mach. Learn., 2 (4):540-556
Seth Reine : University of Texas Southwestern Medical Center - Dallas, TX
Holden Archer : University of Texas Southwestern Medical Center - Dallas, TX
Ahmed Alshaikhsalama : University of Texas Southwestern Medical Center - Dallas, TX
Joel Wells : University of Texas Southwestern Medical Center - Dallas, TX
Ajay Kohli : University of Texas Southwestern Medical Center - Dallas, TX
Louis Vasquez : University of Texas Southwestern Medical Center - Dallas, TX
Allan Hummer : Image Biopsy Labs
Matthew DiFranco : Image Biopsy Labs
Richard Ljuhar : Image Biopsy Labs
Yin Xi : University of Texas Southwestern Medical Center - Dallas, TX
Avneesh Chhabra : University of Texas Southwestern Medical Center - Dallas, TX
DOI: 10.54364/AAIML.2022.1137
Article History: Received on: 06-Dec-22, Accepted on: 12-Dec-22, Published on: 15-Dec-22
Corresponding Author: Seth Reine
Email: seth.reine@utsouthwestern.edu
Citation: Seth Reine, Holden Archer, Ahmed Alshaikhsalama, Joel E Wells, Ajay Kohli, Louis Vazquez, Allan Hummer, Matthew Difranco, Richard Ljuhar, Yin Xi, Avneesh Chhabra (2022). Deep Learning-Generated Radiographic Hip Dysplasia Parameters: Relationship to Postoperative Patient-Reported Outcome Measures. Adv. Artif. Intell. Mach. Learn., 2 (4 ):540-556
Background
Hip
dysplasia (HD) causes accelerated osteoarthrosis of the acetabulum and is
diagnosed through radiographic evaluation. An artificial intelligence (AI) program
capable of measuring the necessary anatomical landmarks relevant to HD could
reduce resource utilization, increase standardized HD screenings, and form HD
outcome models. The study's aim was to evaluate the relationship between AI
measurements of dysplastic hips on initial presentation and changes in patient-reported
outcome measures following surgical intervention for HD.
Methods
One
hundred nine patients with HD and planned surgical intervention obtained
preoperative anterior-posterior pelvic radiographs which were measured by the
HIPPO AI for lateral center edge angle, Tönnis angle, Sharp
angle, Caput-Collum-Diaphyseal angle, femoral coverage, femoral extrusion, and pelvic
obliquity. Patients completed a preoperative survey containing the 12-Item
Short Form, EuroQol Visual Analog Scale (EQVAS), International Hip Outcome Tool
(iHOT-12), Harris Hip Score, and Visual Analog Pain Scales. Patients were
recommended to follow up at four months and one year to complete the same
survey. Changes in outcome measures were evaluated with paired t-tests for each
follow-up interval. Partial Spearman Rank-order correlations were performed
between radiographic measures and changes in outcome measures at each follow-up
interval controlling for age, BMI, and follow-up time.
Results
Patients
had significant improvement in all outcome measures at four months
(N=46,p-values<0.05) and one year (N=49,p-values<0.001), except one-year
EQVAS (p-value=0.090). Significant positive correlation of moderate
strength existed between the Sharp angle and iHOT-12 at four months
postoperatively (rs=0.472,p-value=0.044). No other significant
correlations were found at either follow-up interval between HIPPO measures and
outcome measures.
Conclusion
Correlations
between deep learning radiographic measurements of dysplastic hips and
improvements in postoperative outcomes as evaluated by outcome measures lacked
any significant relationships in this study. Physicians treating HD patients
can augment care with AI tools but outcomes are likely more multi-factorial and
require multi-disciplinary patient care.